Receptor for Advanced Glycation End Product-Dependent Activation of p38 Mitogen-Activated Protein Kinase Contributes to Amyloid-β-Mediated Cortical Synaptic Dysfunction

Soluble amyloid-β (Aβ) peptide is likely to play a key role during early stages of Alzheimer's disease (AD) by perturbing synaptic function and cognitive processes. Receptor for advanced glycation end products (RAGE) has been identified as a receptor involved in Aβ-induced neuronal dysfunction....

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Veröffentlicht in:J Neurosci
Hauptverfasser: Origlia, Nicola, Righi, Massimo, Capsoni, Simona, Cattaneo, Antonino, Fang, Fang, Stern, David M., Chen, John Xi, Schmidt, Ann Marie, Arancio, Ottavio, Yan, Shi Du, Domenici, Luciano
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670592/
https://ncbi.nlm.nih.gov/pubmed/18367618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0204-08.2008
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