Induction of the Phase II Detoxification Pathway Suppresses Neuron Loss in Drosophila Models of Parkinson's Disease

α-Synuclein aggregates are a common feature of sporadic Parkinson's disease (PD), and mutations that increase α-synuclein abundance confer rare heritable forms of PD. Although these findings suggest that α-synuclein plays a central role in the pathogenesis of this disorder, little is known of t...

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Publicat a:J Neurosci
Autors principals: Trinh, Kien, Moore, Katherine, Wes, Paul D., Muchowski, Paul J., Dey, Joyoti, Andrews, Laurie, Pallanck, Leo J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670551/
https://ncbi.nlm.nih.gov/pubmed/18184789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4778-07.2008
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