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GABAergic Depolarization of the Axon Initial Segment in Cortical Principal Neurons Is Caused by the Na–K–2Cl Cotransporter NKCC1

GABAergic terminals of axo-axonic cells (AACs) are exclusively located on the axon initial segment (AIS) of cortical principal neurons, and they are generally thought to exert a powerful inhibitory action. However, recent work (Szabadics et al., 2006) indicates that this input from AACs can be depol...

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Vydáno v:J Neurosci
Hlavní autoři: Khirug, Stanislav, Yamada, Junko, Afzalov, Ramil, Voipio, Juha, Khiroug, Leonard, Kaila, Kai
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670448/
https://ncbi.nlm.nih.gov/pubmed/18448640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0908-08.2008
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