Ceramide Is Responsible for the Failure of Compensatory Nerve Sprouting in Apolipoprotein E Knock-Out Mice

Apolipoprotein E (apoE) is a key transporter of the cholesterol and phospholipids required for membrane synthesis and nerve growth. We now report a virtual absence in apoE knock-out (KO) mice of normal nerve growth factor (NGF)-driven compensatory sprouting of undamaged cutaneous nociceptive nerves....

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Maysinger, Dusica, Holmes, Michael, Han, Xianlin, Epand, Richard M., Pertens, Evi, Foerster, Anne, Barlas, Cia, Holtzman, David M., Diamond, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670367/
https://ncbi.nlm.nih.gov/pubmed/18667621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1461-08.2008
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