Thrombin Induces Long-Term Potentiation of Reactivity to Afferent Stimulation and Facilitates Epileptic Seizures in Rat Hippocampal Slices: Toward Understanding the Functional Consequences of Cerebrovascular Insults

The effects of thrombin, a blood coagulation serine protease, were studied in rat hippocampal slices, in an attempt to comprehend its devastating effects when released into the brain after stroke and head trauma. Thrombin acting through its receptor, protease-activated receptor 1 (PAR1), produced a...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Maggio, Nicola, Shavit, Efrat, Chapman, Joab, Segal, Menahem
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2008
Fag:
Brief Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670357/
https://ncbi.nlm.nih.gov/pubmed/18199772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3665-07.2008
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