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Glial Dysfunction in Parkin Null Mice: Effects of Aging

Parkin mutations in humans produce parkinsonism whose pathogenesis is related to impaired protein degradation, increased free radicals, and abnormal neurotransmitter release. The role of glia in parkin deficiency is little known. We cultured midbrain glia from wild-type (WT) and parkin knock-out (PK...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Solano, Rosa M., Casarejos, Maria J., Menéndez-Cuervo, Jamie, Rodriguez-Navarro, Jose A., García de Yébenes, Justo, Mena, Maria A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670347/
https://ncbi.nlm.nih.gov/pubmed/18199761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4609-07.2008
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