Melatonin Prevents Mice Cortical Astrocytes From Hemin-Induced Toxicity Through Activating PKCα/Nrf2/HO-1 Signaling in vitro

Secondary injuries mediated by oxidative stress lead to deterioration of neurological functions after intracerebral hemorrhage (ICH). Cortical astrocytes are among the most important cells in the central nervous system (CNS), and play key roles in maintaining redox homeostasis by providing oxidative...

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Bibliographic Details
Published in:Front Neurosci
Main Authors: Chen, Xiao, Xi, Zhiyu, Liang, Huaibin, Sun, Yuhao, Zhong, Zhihong, Wang, Baofeng, Bian, Liuguan, Sun, Qingfang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669962/
https://ncbi.nlm.nih.gov/pubmed/31404262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00760
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