Anthocyanin Delphinidin Prevents Neoplastic Transformation of Mouse Skin JB6 P+ Cells: Epigenetic Re-activation of Nrf2-ARE Pathway

Redox imbalance is a major contributor to the pathogenesis of melanoma and nonmelanoma skin cancer. Activation of the nuclear factor E2-related factor 2 (Nrf2)-antioxidant responsive element (ARE) pathway is an intrinsic defense mechanism against oxidative stress. Flavonoids such as anthocyanidins,...

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Bibliografische gegevens
Gepubliceerd in:AAPS J
Hoofdauteurs: Kuo, Hsiao-Chen, Wu, Renyi, Li, Shanyi, Yang, Anne Yuqing, Kong, Ah-Ng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669902/
https://ncbi.nlm.nih.gov/pubmed/31254216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-019-0355-5
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