Blocking of JB6 Cell Transformation by Tanshinone IIA: Epigenetic Reactivation of Nrf2 Antioxidative Stress Pathway

Increasing numbers of natural products have been found to possess anticancer effects. Nuclear factor erythroid-2-related factor-2 (Nrf2) is a master regulator of the antioxidative stress response, and our previous studies found that epigenetic modification of the Nrf2 gene appears to be a critical m...

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Bibliographic Details
Published in:AAPS J
Main Authors: Wang, Ling, Zhang, Chengyue, Guo, Yue, Su, Zheng-Yuan, Yang, Yuqing, Shu, Limin, Kong, Ah-Ng Tony
Format: Artigo
Language:Inglês
Published: Springer US 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389756/
https://ncbi.nlm.nih.gov/pubmed/25274607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9666-8
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