Elucidating the Role of the Maternal Embryonic Leucine Zipper Kinase in Adrenocortical Carcinoma

Adrenocortical carcinoma (ACC) is an aggressive cancer with a 5-year survival rate <35%. Mortality remains high due to lack of targeted therapies. Using bioinformatic analyses, we identified maternal embryonic leucine zipper kinase (MELK) as 4.1-fold overexpressed in ACC compared with normal adre...

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Veröffentlicht in:Endocrinology
Hauptverfasser: Kiseljak-Vassiliades, Katja, Zhang, Yu, Kar, Adwitiya, Razzaghi, Raud, Xu, Mei, Gowan, Katherine, Raeburn, Christopher D, Albuja-Cruz, Maria, Jones, Kenneth L, Somerset, Hilary, Fishbein, Lauren, Leong, Stephen, Wierman, Margaret E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2018
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669820/
https://ncbi.nlm.nih.gov/pubmed/29790920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00310
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