Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers

IMPORTANCE: Increasing evidence suggests an important role of liver function in the pathophysiology of Alzheimer disease (AD). The liver is a major metabolic hub; therefore, investigating the association of liver function with AD, cognition, neuroimaging, and CSF biomarkers would improve the underst...

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Vydáno v:JAMA Netw Open
Hlavní autoři: Nho, Kwangsik, Kueider-Paisley, Alexandra, Ahmad, Shahzad, MahmoudianDehkordi, Siamak, Arnold, Matthias, Risacher, Shannon L., Louie, Gregory, Blach, Colette, Baillie, Rebecca, Han, Xianlin, Kastenmüller, Gabi, Trojanowski, John Q., Shaw, Leslie M., Weiner, Michael W., Doraiswamy, P. Murali, van Duijn, Cornelia, Saykin, Andrew J., Kaddurah-Daouk, Rima
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2019
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669786/
https://ncbi.nlm.nih.gov/pubmed/31365104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2019.7978
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