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Assays for Determining Pertussis Toxin Activity in Acellular Pertussis Vaccines

Whooping cough is caused by the bacterium Bordetella pertussis. There are currently two types of vaccines that can prevent the disease; whole cell vaccines (WCV) and acellular vaccines (ACV). The main virulence factor produced by the organism is pertussis toxin (PTx). This toxin is responsible for m...

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Bibliographic Details
Published in:Toxins (Basel)
Main Authors: Markey, Kevin, Asokanathan, Catpagavalli, Feavers, Ian
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669641/
https://ncbi.nlm.nih.gov/pubmed/31319496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11070417
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