Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39

OBJECTIVES: We sought to investigate whether genetic effects on response to TNF inhibitors (TNFi) in rheumatoid arthritis (RA) could be localised by considering known genetic susceptibility loci for relevant traits and to evaluate the usefulness of these genetic loci for stratifying drug response. M...

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Veröffentlicht in:Ann Rheum Dis
Hauptverfasser: Spiliopoulou, Athina, Colombo, Marco, Plant, Darren, Nair, Nisha, Cui, Jing, Coenen, Marieke JH, Ikari, Katsunori, Yamanaka, Hisashi, Saevarsdottir, Saedis, Padyukov, Leonid, Bridges Jr., S Louis, Kimberly, Robert P, Okada, Yukinori, van Riel, Piet L CM, Wolbink, Gertjan, van der Horst-Bruinsma, Irene E, de Vries, Niek, Tak, Paul P, Ohmura, Koichiro, Canhão, Helena, Guchelaar, Henk-Jan, Huizinga, Tom WJ, Criswell, Lindsey A, Raychaudhuri, Soumya, Weinblatt, Michael E, Wilson, Anthony G, Mariette, Xavier, Isaacs, John D, Morgan, Ann W, Pitzalis, Costantino, Barton, Anne, McKeigue, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2019
Schlagworte:
Rheumatoid Arthritis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669378/
https://ncbi.nlm.nih.gov/pubmed/31036624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-214877
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