Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39

OBJECTIVES: We sought to investigate whether genetic effects on response to TNF inhibitors (TNFi) in rheumatoid arthritis (RA) could be localised by considering known genetic susceptibility loci for relevant traits and to evaluate the usefulness of these genetic loci for stratifying drug response. M...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Spiliopoulou, Athina, Colombo, Marco, Plant, Darren, Nair, Nisha, Cui, Jing, Coenen, Marieke JH, Ikari, Katsunori, Yamanaka, Hisashi, Saevarsdottir, Saedis, Padyukov, Leonid, Bridges Jr., S Louis, Kimberly, Robert P, Okada, Yukinori, van Riel, Piet L CM, Wolbink, Gertjan, van der Horst-Bruinsma, Irene E, de Vries, Niek, Tak, Paul P, Ohmura, Koichiro, Canhão, Helena, Guchelaar, Henk-Jan, Huizinga, Tom WJ, Criswell, Lindsey A, Raychaudhuri, Soumya, Weinblatt, Michael E, Wilson, Anthony G, Mariette, Xavier, Isaacs, John D, Morgan, Ann W, Pitzalis, Costantino, Barton, Anne, McKeigue, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Rheumatoid Arthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669378/
https://ncbi.nlm.nih.gov/pubmed/31036624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-214877
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