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Sugar Modification Enhances Cytotoxic Activity of PAMAM-Doxorubicin Conjugate in Glucose-Deprived MCF-7 Cells – Possible Role of GLUT1 Transporter

PURPOSE: In order to overcome the obstacles and side effects of classical chemotherapy, numerous studies have been performed to develop the treatment based on targeted transport of active compounds directly to the site of action. Since tumor cells are featured with intensified glucose metabolism, we...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Pharm Res
Päätekijät: Sztandera, Krzysztof, Działak, Paula, Marcinkowska, Monika, Stańczyk, Maciej, Gorzkiewicz, Michał, Janaszewska, Anna, Klajnert-Maculewicz, Barbara
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669199/
https://ncbi.nlm.nih.gov/pubmed/31367876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-019-2673-9
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