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Sugar Modification Enhances Cytotoxic Activity of PAMAM-Doxorubicin Conjugate in Glucose-Deprived MCF-7 Cells – Possible Role of GLUT1 Transporter

PURPOSE: In order to overcome the obstacles and side effects of classical chemotherapy, numerous studies have been performed to develop the treatment based on targeted transport of active compounds directly to the site of action. Since tumor cells are featured with intensified glucose metabolism, we...

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Publicat a:Pharm Res
Autors principals: Sztandera, Krzysztof, Działak, Paula, Marcinkowska, Monika, Stańczyk, Maciej, Gorzkiewicz, Michał, Janaszewska, Anna, Klajnert-Maculewicz, Barbara
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669199/
https://ncbi.nlm.nih.gov/pubmed/31367876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-019-2673-9
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