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Effects of Renal Impairment on the Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets

BACKGROUND: An extended-release formulation of amantadine (Osmolex ER™, Osmotica Pharmaceutical US LLC) was approved in February 2018 to treat Parkinson’s disease and drug-induced extrapyramidal reactions in adults. OBJECTIVES: To determine the pharmacokinetic profile of extended-release amantadine...

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Detalhes bibliográficos
Publicado no:CNS Drugs
Main Authors: deVries, Tina, Dentiste, Angela, Di Lea, Clifford, Pichette, Vincent, Jacobs, David
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669187/
https://ncbi.nlm.nih.gov/pubmed/31342404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40263-019-00651-1
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