Golgi phosphoprotein 3 sensitizes the tumour suppression effect of gefitinib on gliomas

OBJECTIVES: We previously reported that Golgi phosphoprotein 3 (GOLPH3) promotes glioma progression by inhibiting EGFR endocytosis and degradation, leading to EGFR accumulation and PI3K‐AKT pathway over‐activation. In the current study, we examine whether GOLPH3 affects the response of glioma cells...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Wang, Xu, Wang, Zhaohao, Zhang, Yu, Wang, Yan, Zhang, Hao, Xie, Shao, Xie, Peng, Yu, Rutong, Zhou, Xiuping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669003/
https://ncbi.nlm.nih.gov/pubmed/31094020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12636
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