Golgi phosphoprotein 3 sensitizes the tumour suppression effect of gefitinib on gliomas

OBJECTIVES: We previously reported that Golgi phosphoprotein 3 (GOLPH3) promotes glioma progression by inhibiting EGFR endocytosis and degradation, leading to EGFR accumulation and PI3K‐AKT pathway over‐activation. In the current study, we examine whether GOLPH3 affects the response of glioma cells...

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Dades bibliogràfiques
Publicat a:Cell Prolif
Autors principals: Wang, Xu, Wang, Zhaohao, Zhang, Yu, Wang, Yan, Zhang, Hao, Xie, Shao, Xie, Peng, Yu, Rutong, Zhou, Xiuping
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669003/
https://ncbi.nlm.nih.gov/pubmed/31094020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12636
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