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EXTH-16. GOLPH3 SENSITIZES THE TUMOR SUPPRESSION EFFECT OF GEFITINIB ON GLIOMAS
Golgi phosphoprotein 3 (GOLPH3) is associated with worse prognosis of gliomas, but its role and mechanism in glioma progression remain largely unknown. We previously reported that GOLPH3 promotes glioma progression by inhibiting EGFR endocytosis and degradation, leading to EGFR accumulation and PI3K...
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| Publicado no: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217115/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.365 |
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