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Direct resequencing of the complete ERBB2 coding sequence reveals an absence of activating mutations in ERBB2 amplified breast cancer.
Gene amplification is among the most common cytogenetic abnormalities that cause cancer. One of the most clinically important gene amplifications in human cancer causes extensive reduplication of ERBB2 (ERBB2). A variety of cancers also occasionally harbor somatic mutations in ERBB2. Gene amplificat...
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| Publié dans: | Genes Chromosomes Cancer |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6668724/ https://ncbi.nlm.nih.gov/pubmed/18418848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20566 |
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