Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss

Pericytes are positioned between brain capillary endothelial cells, astrocytes and neurons. They degenerate in multiple neurological disorders. However, their role in the pathogenesis of these disorders remains debatable. Here, we generated an inducible pericyte-specific Cre line and crossed pericyt...

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Bibliographic Details
Published in:Nat Neurosci
Main Authors: Nikolakopoulou, Angeliki M., Montagne, Axel, Kisler, Kassandra, Dai, Zhonghua, Wang, Yaoming, Huuskonen, Mikko T., Sagare, Abhay P., Lazic, Divna, Sweeney, Melanie D., Kong, Pan, Wang, Min, Owens, Nelly Chuqui, Lawson, Erica J., Xie, Xiaochun, Zhao, Zhen, Zlokovic, Berislav V.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668719/
https://ncbi.nlm.nih.gov/pubmed/31235908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-019-0434-z
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