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Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosis
The migration of leukocytes into the CNS drives the neuropathology of multiple sclerosis (MS). It is likely that this penetration utilizes energy resources that remain to be defined. Using the experimental autoimmune encephalomyelitis (EAE) model of MS, we determined that macrophages within the peri...
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| Pubblicato in: | J Clin Invest |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6668690/ https://ncbi.nlm.nih.gov/pubmed/31112527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124012 |
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