Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosis

The migration of leukocytes into the CNS drives the neuropathology of multiple sclerosis (MS). It is likely that this penetration utilizes energy resources that remain to be defined. Using the experimental autoimmune encephalomyelitis (EAE) model of MS, we determined that macrophages within the peri...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Kaushik, Deepak Kumar, Bhattacharya, Anindita, Mirzaei, Reza, Rawji, Khalil S., Ahn, Younghee, Rho, Jong M., Yong, V. Wee
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668690/
https://ncbi.nlm.nih.gov/pubmed/31112527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124012
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