Antibiotic pretreatment alleviates liver transplant damage in mice and humans

Although modifications of gut microbiota with antibiotics (Abx) influence mouse skin and cardiac allografts, its role in orthotopic liver transplantation (OLT) remains unknown. We aimed to determine whether and how recipient Abx pretreatment may affect hepatic ischemia-reperfusion injury (IRI) and O...

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Udgivet i:J Clin Invest
Main Authors: Nakamura, Kojiro, Kageyama, Shoichi, Ito, Takahiro, Hirao, Hirofumi, Kadono, Kentaro, Aziz, Antony, Dery, Kenneth J., Everly, Matthew J., Taura, Kojiro, Uemoto, Shinji, Farmer, Douglas G., Kaldas, Fady M., Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668671/
https://ncbi.nlm.nih.gov/pubmed/31329160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127550
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