Role of Hypoxia Inducible Factor-1 Alpha (HIF-1α) in Cytoglobin Expression and Fibroblast Proliferation of Keloids

BACKGROUND: Keloids are characterized by an overabundance of collagen deposition due to elevated activity and proliferation of fibroblasts, which lead to hypoxic conditions. Adaptation to these conditions is regulated by the transcription factor hypoxia inducible factor-1α (HIF-1α). Cytoglobin (Cygb...

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Udgivet i:Kobe J Med Sci
Main Authors: JUSMAN, SRI WIDIA A., SARI, DEWI HAMBAR, NINGSIH, SRI SUCIATI, HARDIANY, NOVI SILVIA, SADIKIN, MOHAMAD
Format: Artigo
Sprog:Inglês
Udgivet: Kobe University School Of Medicine 2019
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668593/
https://ncbi.nlm.nih.gov/pubmed/31341152
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