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Role of Hypoxia Inducible Factor-1 Alpha (HIF-1α) in Cytoglobin Expression and Fibroblast Proliferation of Keloids

BACKGROUND: Keloids are characterized by an overabundance of collagen deposition due to elevated activity and proliferation of fibroblasts, which lead to hypoxic conditions. Adaptation to these conditions is regulated by the transcription factor hypoxia inducible factor-1α (HIF-1α). Cytoglobin (Cygb...

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Publicado en:Kobe J Med Sci
Main Authors: JUSMAN, SRI WIDIA A., SARI, DEWI HAMBAR, NINGSIH, SRI SUCIATI, HARDIANY, NOVI SILVIA, SADIKIN, MOHAMAD
Formato: Artigo
Idioma:Inglês
Publicado: Kobe University School Of Medicine 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668593/
https://ncbi.nlm.nih.gov/pubmed/31341152
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