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Role of Hypoxia Inducible Factor-1 Alpha (HIF-1α) in Cytoglobin Expression and Fibroblast Proliferation of Keloids
BACKGROUND: Keloids are characterized by an overabundance of collagen deposition due to elevated activity and proliferation of fibroblasts, which lead to hypoxic conditions. Adaptation to these conditions is regulated by the transcription factor hypoxia inducible factor-1α (HIF-1α). Cytoglobin (Cygb...
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Publicado en: | Kobe J Med Sci |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
Kobe University School Of Medicine
2019
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6668593/ https://ncbi.nlm.nih.gov/pubmed/31341152 |
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