Pyrosequencing versus methylation-specific PCR for assessment of MGMT methylation in tumor and blood samples of glioblastoma patients

Circulating biomarkers in blood may provide an interesting alternative to risky tissue biopsies in the diagnosis and follow-up of glioblastoma patients. We have assessed MGMT methylation status in blood and tissue samples from unresected glioblastoma patients who had been included in the randomized...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Estival, Anna, Sanz, Carolina, Ramirez, Jose-Luis, Velarde, Jose Maria, Domenech, Marta, Carrato, Cristina, de las Peñas, Ramón, Gil-Gil, Miguel, Sepúlveda, Juan, Armengol, Roser, Cardiel, Isaac, Berrocal, Alfonso, Luque, Raquel, Herrero, Ana, Balana, Carmen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668570/
https://ncbi.nlm.nih.gov/pubmed/31366977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47642-2
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