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Detection of MGMT promoter methylation in glioblastoma using pyrosequencing

Recent clinical trials on patients with glioblastoma revealed that O6-Methylguanine-DNA methyltransferase (MGMT) methylation status significantly predicts patient’s response to alkylating agents. In this study, we sought to develop and validate a quantitative MGMT methylation assay using pyrosequenc...

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Bibliografiska uppgifter
I publikationen:Int J Clin Exp Pathol
Huvudupphovsmän: Xie, Hao, Tubbs, Raymond, Yang, Bin
Materialtyp: Artigo
Språk:Inglês
Publicerad: e-Century Publishing Corporation 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396208/
https://ncbi.nlm.nih.gov/pubmed/25973069
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