Potential population level impact on tuberculosis incidence of using an mRNA expression signature correlate-of-risk test to target tuberculosis preventive therapy

Achieving the WHO End-Tuberculosis (TB) targets requires approaches to prevent progression to TB among individuals with Mycobacterium tuberculosis (M.tb) infection. Effective preventive therapy (PT) exists, but current tests have low specificity for identifying who, among those infected, is at risk...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Sumner, Tom, Scriba, Thomas J., Penn-Nicholson, Adam, Hatherill, Mark, White, Richard G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668474/
https://ncbi.nlm.nih.gov/pubmed/31366947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47645-z
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