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Potential population level impact on tuberculosis incidence of using an mRNA expression signature correlate-of-risk test to target tuberculosis preventive therapy

Achieving the WHO End-Tuberculosis (TB) targets requires approaches to prevent progression to TB among individuals with Mycobacterium tuberculosis (M.tb) infection. Effective preventive therapy (PT) exists, but current tests have low specificity for identifying who, among those infected, is at risk...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sumner, Tom, Scriba, Thomas J., Penn-Nicholson, Adam, Hatherill, Mark, White, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668474/
https://ncbi.nlm.nih.gov/pubmed/31366947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47645-z
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