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Influence of CYP3A5 and ABCB1 Polymorphism on Tacrolimus Drug Dosing in South Indian Renal Allograft Recipients

INTRODUCTION: Tacrolimus blood levels are influenced by polymorphisms involving Cytochrome 3A subfamily (CYP3A5) and P-Glycoprotein (ABCB-1) genes. However, their role in transplant outcomes was less studied in South Indian population. We studied the prevalence and impact of these polymorphisms in r...

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Detalhes bibliográficos
Publicado no:Indian J Nephrol
Main Authors: Fernando, M. Edwin, Sellappan, Manokaran, Srinivasa Prasad, N. D., Suren, Sujit, Thirumalvalavan, K
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer - Medknow 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668310/
https://ncbi.nlm.nih.gov/pubmed/31423060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/ijn.IJN_97_18
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