G(αq) Sensitizes TRPM8 to Inhibition by PI(4,5)P(2) Depletion upon Receptor Activation

The cold- and menthol-sensitive transient receptor potential melastatin 8 (TRPM8) channel is important for both physiological temperature detection and cold allodynia. Activation of G-protein-coupled receptors (GPCRs) by proinflammatory mediators inhibits these channels. It was proposed that this in...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Liu, Luyu, Yudin, Yevgen, Nagwekar, Janhavi, Kang, Chifei, Shirokova, Natalia, Rohacs, Tibor
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668199/
https://ncbi.nlm.nih.gov/pubmed/31127000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2304-18.2019
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge