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Bruton’s tyrosine kinase is at the crossroads of metabolic adaptation in primary malignant human lymphocytes

In this work we explored metabolic aspects of human primary leukemic lymphocytes that hold a potential impact on the treatment of Bruton tyrosine kinase (BTK)-driven diseases. Our results suggest that there is crosstalk between Bruton tyrosine kinase (BTK) signaling and bioenergetic stress responses...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sharif-Askari, Bahram, Doyon, Daniel, Paliouras, Miltiadis, Aloyz, Raquel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667467/
https://ncbi.nlm.nih.gov/pubmed/31363127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47305-2
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