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Rational Reprogramming of Cellular States by Combinatorial Perturbation
Ectopic expression of transcription factors (TFs) can reprogram cell state. However, because of the large combinatorial space of possible TF cocktails, it remains difficult to identify TFs that reprogram specific cell types. Here, we develop Reprogram-Seq to experimentally screen thousands of TF coc...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6667192/ https://ncbi.nlm.nih.gov/pubmed/31216470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.05.079 |
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