Microglia Protect Neurons against Ischemia by Synthesis of Tumor Necrosis Factor

Microglia and infiltrating leukocytes are considered major producers of tumor necrosis factor (TNF), which is a crucial player in cerebral ischemia and brain inflammation. We have identified a neuroprotective role for microglial-derived TNF in cerebral ischemia in mice. We show that cortical infarct...

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Publicat a:J Neurosci
Autors principals: Lambertsen, Kate Lykke, Clausen, Bettina Hjelm, Babcock, Alicia Anne, Gregersen, Rikke, Fenger, Christina, Nielsen, Helle Hvilsted, Haugaard, Laila Skov, Wirenfeldt, Martin, Nielsen, Marianne, Dagnaes-Hansen, Frederik, Bluethmann, Horst, Færgeman, Nils Joakim, Meldgaard, Michael, Deierborg, Tomas, Finsen, Bente
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2009
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6666095/
https://ncbi.nlm.nih.gov/pubmed/19193879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5505-08.2009
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