Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice

BACKGROUND: Interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) are expressed by microglia and infiltrating macrophages following ischemic stroke. Whereas IL-1β is primarily neurotoxic in ischemic stroke, TNF-α may have neurotoxic and/or neuroprotective effects. We investigated whether IL-1β...

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Hauptverfasser: Clausen, Bettina H, Lambertsen, Kate L, Babcock, Alicia A, Holm, Thomas H, Dagnaes-Hansen, Frederik, Finsen, Bente
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585073/
https://ncbi.nlm.nih.gov/pubmed/18947400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-46
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