Genetic ablation of soluble tumor necrosis factor with preservation of membrane tumor necrosis factor is associated with neuroprotection after focal cerebral ischemia

Microglia respond to focal cerebral ischemia by increasing their production of the neuromodulatory cytokine tumor necrosis factor, which exists both as membrane-anchored tumor necrosis factor and as cleaved soluble tumor necrosis factor forms. We previously demonstrated that tumor necrosis factor kn...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Madsen, Pernille M, Clausen, Bettina H, Degn, Matilda, Thyssen, Stine, Kristensen, Lotte K, Svensson, Martina, Ditzel, Nicholas, Finsen, Bente, Deierborg, Tomas, Brambilla, Roberta, Lambertsen, Kate L
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012516/
https://ncbi.nlm.nih.gov/pubmed/26661199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X15610339
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