Sustained Axon–Glial Signaling Induces Schwann Cell Hyperproliferation, Remak Bundle Myelination, and Tumorigenesis

Type III neuregulins exposed on axon surfaces control myelination of the peripheral nervous system. It has been shown, for example, that threshold levels of type III β1a neuregulin dictate not only the myelination fate of axons but also myelin thickness. Here we show that another neuregulin isoform,...

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Published in:J Neurosci
Main Authors: Gomez-Sanchez, Jose A., Lopez de Armentia, Mikel, Lujan, Rafael, Kessaris, Nicoletta, Richardson, William D., Cabedo, Hugo
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665929/
https://ncbi.nlm.nih.gov/pubmed/19741137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1753-09.2009
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