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Basal Forebrain Lactate Release and Promotion of Cortical Arousal during Prolonged Waking Is Attenuated in Aging

The wake-promoting basal forebrain (BF) is critically involved in sustaining cortical arousal. In the present study, we investigated how aging affects the capacity of the BF to cope with continuous activation during prolonged waking. Increased neuronal activity induces lactate release in the activat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Wigren, Henna-Kaisa, Rytkönen, Kirsi-Marja, Porkka-Heiskanen, Tarja
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665766/
https://ncbi.nlm.nih.gov/pubmed/19759316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5773-08.2009
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