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Basal Forebrain Lactate Release and Promotion of Cortical Arousal during Prolonged Waking Is Attenuated in Aging

The wake-promoting basal forebrain (BF) is critically involved in sustaining cortical arousal. In the present study, we investigated how aging affects the capacity of the BF to cope with continuous activation during prolonged waking. Increased neuronal activity induces lactate release in the activat...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Wigren, Henna-Kaisa, Rytkönen, Kirsi-Marja, Porkka-Heiskanen, Tarja
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665766/
https://ncbi.nlm.nih.gov/pubmed/19759316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5773-08.2009
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