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Psychosine Accumulates in Membrane Microdomains in the Brain of Krabbe Patients, Disrupting the Raft Architecture

Lipid rafts (LRs) are membrane realms characterized by high concentrations of cholesterol and sphingolipids. Often, they are portrayed as scaffolds on which many different signaling molecules can assemble their cascades. The idea of rafts as scaffolds is garnering significant attention as the conseq...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: White, Adam B., Givogri, Maria I., Lopez-Rosas, Aurora, Cao, Hongmei, van Breemen, Richard, Thinakaran, Gopal, Bongarzone, Ernesto R.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665501/
https://ncbi.nlm.nih.gov/pubmed/19439584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5597-08.2009
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