Psychosine Accumulates in Membrane Microdomains in the Brain of Krabbe Patients, Disrupting the Raft Architecture

Lipid rafts (LRs) are membrane realms characterized by high concentrations of cholesterol and sphingolipids. Often, they are portrayed as scaffolds on which many different signaling molecules can assemble their cascades. The idea of rafts as scaffolds is garnering significant attention as the conseq...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: White, Adam B., Givogri, Maria I., Lopez-Rosas, Aurora, Cao, Hongmei, van Breemen, Richard, Thinakaran, Gopal, Bongarzone, Ernesto R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665501/
https://ncbi.nlm.nih.gov/pubmed/19439584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5597-08.2009
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