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Kinase-Dead Knock-In Mouse Reveals an Essential Role of Kinase Activity of Ca(2+)/Calmodulin-Dependent Protein Kinase IIα in Dendritic Spine Enlargement, Long-Term Potentiation, and Learning
Ca(2+)/calmodulin-dependent protein kinase IIα (CaMKIIα) is an essential mediator of activity-dependent synaptic plasticity that possesses multiple protein functions. So far, the autophosphorylation site-mutant mice targeted at T286 and at T305/306 have demonstrated the importance of the autonomous...
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| Yayımlandı: | J Neurosci |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Society for Neuroscience
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6665418/ https://ncbi.nlm.nih.gov/pubmed/19515929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0707-09.2009 |
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