Načítá se...

Dysregulation of Iron Homeostasis in the CNS Contributes to Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS), characterized by degeneration of spinal motor neurons, consists of sporadic and familial forms. One cause of familial ALS is missense mutations in the superoxide dismutase 1 (SOD1) gene. Iron accumulation occurs in the CNS of both forms of ALS; however, its contr...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Jeong, Suh Young, Rathore, Khizr I., Schulz, Katrin, Ponka, Prem, Arosio, Paolo, David, Samuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665152/
https://ncbi.nlm.nih.gov/pubmed/19158288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5443-08.2009
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!