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Dysregulation of Iron Homeostasis in the CNS Contributes to Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS), characterized by degeneration of spinal motor neurons, consists of sporadic and familial forms. One cause of familial ALS is missense mutations in the superoxide dismutase 1 (SOD1) gene. Iron accumulation occurs in the CNS of both forms of ALS; however, its contr...

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Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Jeong, Suh Young, Rathore, Khizr I., Schulz, Katrin, Ponka, Prem, Arosio, Paolo, David, Samuel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665152/
https://ncbi.nlm.nih.gov/pubmed/19158288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5443-08.2009
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