Mature BDNF, But Not proBDNF, Reduces Excitability of Fast-Spiking Interneurons in Mouse Dentate Gyrus

Mature BDNF and its precursor proBDNF may both be secreted to exert opposite effects on synaptic plasticity in the hippocampus. However, it is unknown how proBDNF and mature BDNF affect the excitability of GABAergic interneurons and thereby regulate GABAergic inhibition. We made recordings of GABAer...

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Publicat a:J Neurosci
Autors principals: Holm, Mai Marie, Nieto-Gonzalez, Jose Luis, Vardya, Irina, Vaegter, Christian Bjerggaard, Nykjaer, Anders, Jensen, Kimmo
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2009
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665103/
https://ncbi.nlm.nih.gov/pubmed/19812317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2978-09.2009
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