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High temperature suppressed SSC self-renewal through S phase cell cycle arrest but not apoptosis
BACKGROUND: High temperature has a very adverse effect on mammalian spermatogenesis and eventually leads to sub- or infertility through either apoptosis or DNA damage. However, the direct effects of heat stress on the development of spermatogonial stem cells (SSCs) are still unknown because SSCs are...
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| Опубликовано в: : | Stem Cell Res Ther |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6664773/ https://ncbi.nlm.nih.gov/pubmed/31358059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1335-5 |
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