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High temperature suppressed SSC self-renewal through S phase cell cycle arrest but not apoptosis

BACKGROUND: High temperature has a very adverse effect on mammalian spermatogenesis and eventually leads to sub- or infertility through either apoptosis or DNA damage. However, the direct effects of heat stress on the development of spermatogonial stem cells (SSCs) are still unknown because SSCs are...

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Dades bibliogràfiques
Publicat a:Stem Cell Res Ther
Autors principals: Wang, Jia, Gao, Wei-Jun, Deng, Shou-Long, Liu, Xiang, Jia, Hua, Ma, Wen-Zhi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664773/
https://ncbi.nlm.nih.gov/pubmed/31358059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1335-5
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