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A novel method for conjugating the terminal amine of peptide ligands to cholesterol: synthesis iRGD-cholesterol
AIM: Conventional conjugation reactions often involve the use of activated PEG as a linker, but concerns about PEG-mediated reduction in intracellular delivery and enhanced immunogenicity have generated interest in developing methods that eliminate the need for a PEG linker. MATERIALS & METHODS:...
Guardat en:
| Publicat a: | Ther Deliv |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Future Science Ltd
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6664274/ https://ncbi.nlm.nih.gov/pubmed/30730822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/tde-2018-0057 |
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