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RIP2 promotes FcγR-mediated reactive oxygen species production

Receptor-interacting protein 2 (RIP2) is a kinase that mediates signaling downstream of the bacterial peptidoglycan sensors NOD1 and NOD2. Genetic loss or pharmaceutical inhibition of RIP2 has been shown to be beneficial in multiple inflammatory disease models with the effects largely attributed to...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Shehat, Michael G., Cardona, Omar A., Aranjuez, George F., Jewett, Mollie W., Tigno-Aranjuez, Justine T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664193/
https://ncbi.nlm.nih.gov/pubmed/31113864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007218
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